Fulvestrant

Posted on May 14, 2012

Fulvestrant is a potent selective receptor antagonist estrogenic. Manifests its action in the body, not stop production of estrogen, but by preventing it to show their properties. It does this by binding to estrogen receptors in a competitive manner, making them unavailable for estrogen circulating in the blood pool. This kind of action makes it very similar to Nolvadex and Clomid, except that fulvestrant has no agonist properties mixed / atagoniste. It is a pure estrogen receptor antagonist. This preparation is the first antagonist injection type, which attracted the bodybuilders and athletes. Although not widely used, can successfully eliminate adverse effects caused by estrogen, in a course of anabolic steroids and androgens. These side effects are gynecomastia, increased fat and water accumulation in tissues.

Faslodex is a potent antiestrogen, much stronger than Nolvadex and Clomid. Although the targets are receptors for estrogen in the body can create very low estrogen environment, comparable aromatization inhibitors. In one study has shown that it is as effective in fighting breast cancer as Arimidex.

Fulvestrant does not pass into the brain, so lower side effects neural. These effects are hot flushes, mood swings and low energy.

Faslodex has been on the market in 2002, selling in many countries. It comes packaged in pre-filled syringes with a concentration of 50 mg / ml fulvestrant or a 5 ml syringe or two of each 2.5 ml each. The product is kept chilled.

The most common side effects of fulvestrant are met in gastrointestinal disorders such as nausea, vomiting, constipation, abdominal pain and diarrhea. Other common side effects are headache, backache, and sore throat. Side effects are rarely met irritation, weakness, urinary tract irritation, muscle pain, increased liver enzymes. It can also occur at the injection site irritation. Administration by athletes in order to reduce the estrogenic effects of steroids can increase the risk of cardiovascular disease by blocking the beneficial effects that estrogen has on the good cholesterol.

Administration is by intramuscular injection, the dose of 250 mg per month or one-inejctions 5 ml, or two 2.5-ml. Reduced administration (once, maximum twice a month for a 2.5 ml syringe) is an advantage of this antiestrogen.

It is an extremely expensive, less likely to find on the black market.

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Antiestrogens

Posted on May 14, 2012

ADT is an antiestrogen similar in structure with formestane and exemestane. Is part of the powerful anti-estrogen which prevent estrogen formation or in the slightest degree, so the strongest flavored steroids that are banned. Your body needs several days to resume normal production of estrogen after androstatrienedion administration was discontinued.

ADT may be useful to bodybuilders by blocking the negative effects of estrogen when using steroids slightly flavored. Water retention, fat accumulation and gynecomastia can be controlled if properly using such products. The addition of ADT to Naposim cycle of testosterone, for example, may be what will be May Suoranta cycle support and without side effects. Doses are required for visible effects of 50-75 mg / day. Sometimes anti-estrogens are used not to combat the side effects but to weaken and to define. Thus during a cycle of adding ADT’s definition can help in achieving the objective.

Sometimes it is used to end a cycle of steroids to high testosterone levels. Often this process is referred to as post-cycle therapy, stimulators and anti-estrogen used to help restore the body’s normal testosterone production.
Some even use these drugs alone for expanding their testosterone and anabolic effect. But in general this practice is counterproductive for a man with normal testosterone levels.

ADT’s side effects are not significant. Not toxic to the liver, can cause problems in terms of cholesterol, ADT blocking the creation of good cholesterol (HDL). So if you do not follow the total blocking estrogen effects are recommended drugs as Nolvadex or Clomid. The long-term use of potent anti-estrogen such as ADT is not recommended.

As potency is somewhere between formestane and Aromasin. So it is quite powerful but still not enough to price Aromasin. It is a antiestrogen increasingly popular. The main producer of this product is Gaspari Nutrition.

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Tabata method for better results with steroids part 3

Posted on May 13, 2012

Bar will be held in front of body, fingers relaxed, and supported on the collar bar, and elbows in front and high. With feet separated the sides, you just go as low, between them. The lift should not get locked knees at the top, left legs slightly bent, and the movement to be continuous, without breaks in the top or bottom of the exercise.
Weights used to be mild, 30-35 kg in the first trial.

The other exercise is ideal for tabata “engine”. It is one of the best exercises which did not hear anyone from the audience. Take two dumbbells and hold them at shoulder level. Do a squat holding dumbbells on your shoulders, while you lift, push dumbbells up as the shoulder press.

This makes things exercise heart rate and respiration, which honestly can not describe. Again, light weight! Weights of 12 kg are more than sufficient. Maybe two minutes will seem easy, but after these two alone.

Tabata Tips

We need to always have a clock in front during the four minutes of Tabata. And time to have and secondary. Stop after 20 seconds, place the support bar (if you choose genuflexions), rest 10 seconds, and start again. Looking clock seems to help concentration.

And remember this: no need to do other exercises after the Tabata workout. The lungs are screaming like a locomotive. You can choose to do other exercises after, but do not be surprised if you manage to go to the end.

The most difficult thing in this exercise is to remain focused the four minutes. Keep the bar or dumbbells in hand, if possible. After you put the support bar, the State supports it, do not let the hand, and all the while you sit watching the seconds clock.

If you “engine” put weights on a bench, and do not let the hand. Stay ready! This trick seems to make 10 seconds seem a little long, though not long enough, and will help keep the rest in 10 seconds and no more, which is very important.

You can try to do this workout every day, but started training a week is such a success. Why try it? It is probably the best weight loss method ever invented. Even if only four minutes, are so intense that rapid breathing and sweating persist even after their completion.

But above all, Tabata you learn and overcome your limits and stay really focused.

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Tabata method for better results with steroids part 2

Posted on May 13, 2012

It helps to have someone record the reps for each set, that’s because you can not to do after fainting! Use the lowest number of reps performed in a set to compare the evolution of exercise training. If you use too much weight, it could be number 2. If you use too light may be 15.

Before we get to exercise, to clarify exactly what to do. It is not 8 sets of 8 reps. Although the number of 8 repetitions per set of 20 seconds is quite ok. It’s about how many reps you can do in a period of 20 seconds, and then 10 seconds rest.

By the way, 10 seconds, does not mean to put weight back, drinking water, to the game at the beautiful girl next to you, go back to the bar, to focus less and do the next exercise. 10 seconds is 10 seconds, the clock, from the time you finish the previous year. No cheating!

Tabata Exercise

Exercises should be selected using more muscles. They are therefore recommended genuflexions bar in front. For those who protest, why not genuflexions normal bar back, reply is simple: it’s easier to let down when the weight of the front than the back, and start break 10 seconds.

With a military exercise in the press, for example, not using enough muscle to help you to resist the last minute. The shoulders on fire, will not make more than two reps towards the end of training. Statutes have been tried, but greatly increases the risk of injury when performed in Tabata pace.

So genuflexions bar in front are probably the best exercise for Tabata. Besides, if you can not perform well this exercise, Tabata method you will be doing better than you did with 1000 coaches. In four minutes you can do 60-70 reps, which you will learn the central nervous system better than anything.

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Tabata method for better results with steroids part 1

Posted on May 13, 2012

On TV we always see fantastic machine to do exercises that promise fantastic results with just a few minutes a day. I do not debate whether it works or not. Even if it works, as is usually the price. So, in this article will make you save a lot of money, I’ll teach you how to get those fantastic results without expensive machine. This method “top secret” training can do more for you than all the training you have done before, combined. And leave the rest for 23 hours and 56 minutes of the day to do what you want!
But there is a price! Not in money but in exhaustion, vomiting and liters and liters of sweat.

Introduction Tabata method

Tabata is the name of a Japanese researcher who discovered a way to develop both the anaerobic and aerobic capacity while. It is one of those workouts that seem to fit all types of athletes is great for cyclists, for skaters, power-lifters or just common man who wants to lose weight.

This method is so simple and yet so difficult, that athletes tend to try it once to recognize the incredible efficiency and then not mention it again. In what? Simply choose an exact exercise and it thus:
A. 20 seconds, do as many repetitions as possible;
Two. Rest for 10 seconds;
Three. Repeat 7 more times!
That’s all. You finished in 4 minutes. After these four minutes, you will only see in front of the floor, your face will be glued to it.

Eight sets of “as many reps you can do”, with ten seconds rest between them – simplicity and efficiency. The best two Tabata exercises are genuflexions bar in front and “engine”, which I will describe below.

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Information about dianabol steroids

Posted on May 12, 2012

Dianabol is one of the stronger steroids are able to bring large increases in body mass and muscle. Dianabol steroids is one of the first world and Romanian market, but proved to be a powerful steroid that is used today by athletes, bodybuilders and those who want a balanced body with a high percentage of muscle mass and force. Danabol steroid bring rapid increases in weight, but can affect the liver and is therefore recommended that with his administration to use liver protection products such as Liv 52.
Dianabol product is a steroid derived from testosterone that is pronounced anabolic qualities and moderate androgenic qualities.
Balkan Dianabol product is manufactured in Moldova by Balkan Pharmaceuticals company and is 100% original, it is available in pharmacies in Moldova. Product in the form of a box of 3 blisters of 20 tablets of 10mg (60 tablets total dianabol / box) accompanied by a leaflet in Romanian.

Administration: The administration recommended dianabolului desired effects in version 2 to 4 tablets daily, divided on several occasions, and novices are recommended up to 2 tablets daily after the morning meal (first half) and the second half before training daily.
Dianabol steroid used frequently in combination with steroid decadurabolin so it amplifies the effect of decreasing the side effects.
It is recommended that the dianabol cycle length not exceeding 8 weeks break between cycles should be at least 1 month.

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Dianabol information

Posted on May 12, 2012

Dianabol is a powerful steroid that acts both in terms of anabolic and androgenic speaking.

Dianabol recommended daily dose of which has a positive effect without too many side effects is 15-40mg. This steroid is dosed depending on the individual, and those who are beginners they will not use more than 15-20mg. This steroid used frequently in combination with other steroids such as Deca-Durabolin. By combining these two steroids expect large gains muscle mass and strength, without side effects to be pronounced as if they were used only dianabol alone. This steroid is used in cycles of 8 months.

Dianabol steroid also retains a high quantity of water in the body.

The effect of this steroid takes between 3 and 5:00, also is recommended daily dose be administered in two halves to maintain an optimal concentration of substance in the blood for longer.

Although Dianabol can cause some side effects are minimal and rare for a dose of 20 mg / day, the biggest problem when administering Dianabol liver is pretty much required.
Because Dianabol weight increases with water retention can occur and some palpitations increase blood pressure, so it is recommended to administer hypotensive preparation, for example Colefin.

With dianabol use and recommend the use of antiestrogen Nolvadex and Proviron so that Dianabol is almost totally flavor.

As side effects can occur and acne on the body, and if the consumer is genetically predisposed to baldness, it may accelerate it.

A study released in 20mg/day iveana that taking a period of 10 days causes the body to reduce the secretion of testosterone in the body by about 30-40%

After termination of Dianabol cycle will signal a decrease in muscle mass and physical strength.

This steroid can cause people with elevated states agresivity lit temperament.
Dianabol is generally known as a steroid mood of euphoria and can give a better mood that help those using it during training.
In our country this anabolic steroid is known as Naposim.

 

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Different types of hormones

Posted on May 7, 2012

Classification of hormones
Hormones classification is based on range, solubilitat, chemical structure, synthesis and place according to the endocrine system with the nervous interdependinta
Classification of hormones depending on range
Depending on the range of hormones are grouped into:
• local hormones: autocrine and paracrine
• Hormones Endocrine
• neurohormone
Endocrine hormones
Endocrine hormones meet the classical definition is synthesized and secreted by specialized cells will reach the target cell through the circulatory system bound to carrier proteins for hydrophobic or free hormones in blood for hydrophilic hormnilor
Paracrine hormones
Paracrine hormones do not meet the classical definition hormones are synthesized on a specialized cell, uramand act on neighboring cells, without reaching the circulatory torrent Example: D pancreatic cells produced somatostatin acts on cells A (secreting glucagon) and B (secretory insulin) secretion by inhibiting their
Autocrine hormones
Autocrine hormones are synthesized and secreted by one cell into the extracellular space, acting as a messenger on the same cell. In this case the target cell and secretory cell is actually the same cell.
Neurohormones are a special category of chemicals produced by nerve cells in the blood released by axonal endings siapoi carried by the bloodstream to the cell is made target .Within the neurohormonal interaction between the nervous system and endocrine system.
Classification of hormones in function of solubility
Depending on solubility hormones are classified as water soluble hormones (hidrfili) and liposoluble hormones (hibrofobi). Soluble hormones require transport proteins to be carried by blood to the target cell, these hormones also present capacity of cell membrane lipids give traversabistratul, penetrating inside the cell where the specific receprtori be bound to chromatin in the cytoplasm or the nucleus. Free water-soluble hormones travel through the circulatory system but can not cross the cell membrane. Receptors for this hormone was incorporated into cell membranes, causing the production of messengers mates in space at cytoplasmic level messenger hormone is considered primary.
Hydrosoluble hormones
• peptide hormones
• Protein Hormones
• hormones derived from amino acids
Liposoluble hormones
• Steroid hormones
• Thyroid hormones

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About the metabolism

Posted on May 7, 2012

Metabolism and biochemical means all energy transformations that occur in body tissues alive. Metabolism is a complex process, involving exchanges of materials and energy, which includes two processes (simultaneous) opposite:
• catabolism / dezasimilation – all chemical processes of degradation of substances in the body occurs mainly break the carbon atoms in molecules of different substances, this type of reaction is accompanied by release of energy (exothermic reaction).
• anabolism / assimilation – the chemical processes of the biosynthesis of substances that enter into the composition of living matter. Anabolic reactions are characterized by energy and are called endergonice reactions (endothermic reaction).
After his role in the biology of organisms, metabolism is classified into:
• Metabolism primary or fundamental, directly involved, essential in maintaining organisms and plant life.
• Metabolism secondary or side, which is involved in producing substances “essential” life (ie., Pigments, alkaloids, antibiotic agents, etc..).
The energy required for biosynthetic processes comes mostly from the disposal of various compounds macroergice links. Depending on the capacity of energy production, organisms are divided into:
• autotrophic (Greek autos = Himself, trophe = food) – organizations which synthesizes organic substances from inorganic substances required by the process of photosynthesis and chemosinteză.
• heterotrophic (Greek heteros = different, trophe = food) – organizations which provide food using substances synthesized by other organisms (they can be microfage, phytophagous or zoofage).
Catabolism and anabolism takes place through a succession of numerous chemical reactions: hydrolysis, hydrogenation, dehydration, decarboxylation, deamination, transaminare, esterification, condensation polymerization.
Metabolism of drugs and xenobiotics
Metabolism of drug substances and other xenobiotics metabolism includes two main ways:
• Cytochrome P450
• Way flavinmonooxigenazelor
Nitrogen metabolism
Nitrogen metabolism is:
• urea cycle
• Nitrogen Assimilation
• Nitrification
• Denitrification
Energy metabolism – metabolic process which releases energy, chemicals division because their body cells in simple substances.
Metabolism plastic – all responses that contribute to cell construction. (From gr. Plastic – shaped, carved). Examples of plastic metabolism: photosynthesis, chemosynthesis, protein biosynthesis.

 

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Human growth hormone

Posted on May 6, 2012

Hormone (grec. ορμόνη – horman, hormanus – trigger, to awaken) is a biochemical substance that transmits information from one organ or tissue to another, is secreted by the adrenal glands and other tissues to stimulate and coordinate certain organs or whole body.
Unlike the nervous system where information from the center (the brain and spinal cord) impulses nerve axonal extensions or dentric propagate with a speed that takes fractions of a second hormone formations transmitted are slower, some as in the case adrenaline that takes seconds, while for other hormones takes days before information reaches the target tissue or organ.
The exception to this rule are tissue hormones (produced by tissues), hormones such as histamine, serotonin, or prostaglandins, which are produced directly target organ parenchyma.

Hormones have been discovered at the beginning of the century, the term hormone was first used in 1905 by English psychologist Ernest Starling (1866-1927).
Hormones are substances that act on specific target organs, which have special receptors in the cell membrane that binds molecules that hormone, which triggers a series of reactions hormones biochemical, penetrating the cell membrane to reach the cytoplasm, nucleus respectively.

Hormones are produced by animals and endocrine glands: pituitary, epiphysis, thyroid, parathyroid, pancreas, adrenal glands and islets of Langerhans with adrenal, gonads or genital glands.
Name the endocrine glands or glands of internal secretion is because the hormones produced by glands that are shed into the bloodstream is transported by blood to target organ.
Hormones produced by plants are called plant hormones (eg have a core group of a phenolic and steroid group) and similar hormones produced by the animal body, acting at a distance is sufficiently small amounts in the nanogram.
Science dealing with study endocrine and hormone is called endocrinology and doctor endocrinologist working in this field.

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